Solute carrier family 26 member 2 (SLC26A2) is an SO42− transporter, facilitating the uptake of inorganic sulfate into cells.

Melanoma Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects. Melanoma Drugs under development based on the stage of ...

Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, P. R. China ...

The company's lead product candidate, IO102-IO103, which is designed to target immunosuppressive mechanisms mediated by Indoleamine 2,3-dehydrogenase (IDO), and programmed death-ligand (PD-L1 ...

CAS Key Laboratory of Nano-Bio Interface, Suzhou Key Laboratory of Functional Molecular Imaging Technology, Division of Nanobiomedicine and i-Lab, Suzhou Institute of Nano-Tech and Nano-Bionics, ...

吲哚胺 2,3 - 双加氧酶 1（Indoleamine 2,3-dioxygenase 1，IDO1）是一种在免疫调节、肿瘤发生等多种生理病理过程中发挥重要作用的酶。 IDO1 是一种含血红素的单体酶，属于加氧酶家族，能催化色氨酸沿犬尿氨酸途径进行代谢。 人类 IDO1 基因位于 8 号染色体上，编码的 ...

Bladder cancer tissues and immortalized cell lines were used for the following experiments: miR-153 mimics and indoleamine 2,3-dioxygenase 1 (IDO1) siRNA transfection; Western blot, cell viability, ...

Indoleamine 2,3-dioxygenase (IDO), which catalyzes the breakdown of the essential amino acid tryptophan into kynurenine, is understood to have a key role in cancer immunotherapy because of its role in ...