Gene expression data from isolated endodermal cells Data quality was examined using the signal distribution of Affymetrix built-in controls (Spike-in and hybridization controls) using Expression ...

In addition, a subset of data presented in the paper Charting human development using a multi-endodermal organ atlas and organoid models is also included as the example data set for ligand-receptor ...

We identified specific and bright 5-HT-ir within nuclei attributed to a subset of different cell types: ectodermal and endodermal, macro- and micromeres, and blastoderm. Western blot and dot blot ...

The origin of evolutionary novelties is often underpinned by a complex set of changes. The genetic underpinnings comprise, for instance, gene or genome duplication, mutations, deletions, and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cells change their metabolic profiles in ...

The heart is a never-stopping engine that relies on a formidable pool of mitochondria to generate energy and propel pumping. Because dying cardiomyocytes cannot be replaced, this high metabolic rate ...

Dysregulated Wnt signaling is a well-established driver of colorectal carcinogenesis. However, its pivotal role in normal intestinal stem cell homeostasis has posed significant challenges for its ...