Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States Department of Bioengineering, University of California, Los Angeles, California 90095, ...

The DNA sliding clamp proliferating cell nuclear antigen (PCNA) is an essential co-factor for many eukaryotic DNA metabolic enzymes. PCNA is loaded around DNA by the ATP-dependent clamp loader ...

Many microbes and fungi acquire the essential ion Fe 3+ through the synthesis and secretion of high-affinity chelators termed siderophores. In Gram-negative bacteria, these ferric-siderophore ...