2025 年 2 月 17 日，复旦大学生命科学学院王陈继团队、上海市第一妇婴保健院 / 同济大学附属妇产科医院高昆团队合作在 Redox Biology 在线发表了题为 “ The covalent modification of STAT1 cysteines by sulforaphane promotes antitumor immunity via blocking ...

Reactive cysteines on peptide antigens may unlock new cancer immunotherapy possibilities Dec 17, 2024 Therapeutic cancer vaccine may improve tumor response to immune checkpoint blockade treatments ...

This discovery could also advance drug development by identifying reactive cysteines crucial in disease detection and treatment. Chemistry researchers at Case Western Reserve University have ...

The research could also aid drug discovery, as drug developers are looking for reactive cysteines. "Identifying reactive cysteines is central to drug discovery right now," he said. "This could ...

VivosX is an in vivo disulfide crosslinking approach that utilizes a pair of strategically positioned cysteines on two proteins to probe physical interactions within cells. Histone H2A.Z, which often ...

S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6, which modifies key ...