A novel therapeutic showed significant promise in slowing aortic valve calcification, potentially extending time until or eliminating need for transcatheter or surgical intervention for stenosis, ...

A new study published in Mycology highlights the alarming evolutionary rate of Sporothrix, the fungus that causes ...

Background: Heart failure (HF) is a global health concern, affecting millions of individuals worldwide and leading to significant morbidity and mortality. Despite advances in conventional therapeutic ...

Safety of use during pregnancy or breastfeeding is uncertain. These drugs also act to increase intestinal fluid and intestinal movement by targeting receptors called guanylate cyclase-C (GC-C) ...

Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window The nitric oxide-independent soluble guanylate cyclase activator ataciguat continued to show promise for slowing the ...

This process is similar to the PDE5 inhibitors, so these two medicine classes aren't taken together. Adempas (riociguat) is the only drug in its class of soluble guanylate cyclase (sGC) stimulators.

Figure 2: Reduction in heart rate during atrial fibrillation after Gα i2 gene transfer. This study is the first report of intracoronary site-specific gene transfer and the first use of gene ...

Terpenoids constitute one of the largest and most diverse classes of plant metabolites. While some terpenoids are involved in essential plant processes such as photosynthesis, respiration, growth, and ...