India alone has reported over a million AMR-associated deaths in 2019. Carbapenems, a class of antibiotics, often serve as the last line of defence against multi-drug-resistant bacterial infections.

Resistance to carbapenems in Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacteriaceae, mainly determined by the production of carbapenem-hydrolyzing β-lactamases, has emerged ...

The drug also helps preserve the effectiveness of carbapenems, the last-resort antibiotics for many severe infections. There are many more pharmaceuticals in India that are working to fight this.

Medically reviewed by Corinne Savides Happel, MD If you have ever had an allergic reaction to penicillin, you may have been ...

2021). Importantly, in the Enterobacteriaceae family, K. pneumoniae strains that acquire resistance to carbapenems belong to the carbapenem-resistant Enterobacteriaceae (CRE), which are considered a ...

Ertapenem had the highest affinity for those enzymes according to chemical computational study. The synergic effect between ertapenem and others carbapenems against different carbapenemase-producing ...