Phase III REMIX-1 and REMIX-2 trials demonstrated that remibrutinib, an oral BTK inhibitor, significantly reduced chronic ...

Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies, innovations during the past 30 years, ...

Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer immunotherapy.

Chemotaxis is the directional movement of cells in response to a chemical stimulus gradient. Human pathogenic-like Th17 cells express the chemokine receptor CCR6, but how CCR6, together with other ...

Basophils are rare cells in the peripheral blood which have the capability to infiltrate into the skin. Invasion of basophils has been detected in pruritic skin diseases, including atopic dermatitis, ...