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Exp Neurol 296: 1-15. PMID: 28645526 Postdocs' First Author Publications (Since 1993) Boeshore KL, Schreiber RC, Vaccariello SA, Sachs HH, Salazar R, Lee J, Ratan RR, Leahy P, Zigmond RE (2004) Novel ...
We perform submicrometer-scale surgery with femtosecond lasers to study nerve regeneration in the tiny nematode Caenorhabditis elegans, an invertebrate model organism with only 302 neurons. By cutting ...
After axotomy, in the soma-attached proximal axon, axonal regeneration is initiated through mTOR-mediated local axonal translation (Terenzio et al, 2018). More broadly, mTORC1 signaling mediates ...
Kotulska, Katarzyna, Magdalena Larysz-Brysz, Wiesław Marcol, Izabela Malinowska, Iwona Matuszek, Wiesława Grajkowska, and Joanna Lewin-Kowalik. 2006. "Original articleTrkB deficiency increases ...
When a cell sustains damage, it liberates cytosolic ATP, which can serve as an injury signal, affecting neighboring cells. This study presents a methodological approach that employs in vitro axotomy ...
However, we demonstrated in vivo that it was axotomy of the SCG, not deafferentation, which mimicked the effects seen in organ culture. A trivial reason for this finding would have been that axotomy, ...
Disturbance in the neuronal network leads to instability in the microtubule (MT) railroad of axons, causing hindrance in the intra-axonal transport and making it difficult to re-establish the broken ...
The mechanical damage to the axons was recapitulated by puncturing the neuron-laden Matrigel using a pin. Thus, precise axotomy of three-dimensionally aligned axons could be performed. Furthermore, it ...
Axotomy resulted in increased fission and attempted fission events in control YFP-Drp1 expressing neurons (Figures 5F,G). The increases in fission and attempted fission events in response to axotomy ...
Curiously, recordings performed after axotomy in hypoglossal motoneurons found suppression of IPSPs in many motoneurons and their replacement by EPSPs (Takata and Nagahama, 1983). This was interpreted ...
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