Rare eye diseases are the leading cause of untreatable blindness in Europe and affect people of all ages. The RESTORE VISION scientific team has identified seven rare ocular conditions that impact the ...

In vivo laser axotomy of a single subbasal fiber (SBF) in an adult mouse. The Ocular Neurobiology laboratory at the Institute for Neurosciences, a joint center of Miguel Hernández University (UMH ...

Figure 1: Neuroprotection by bFGF is associated with increased expression of activin βA mRNA. Recently, a different type of interaction between bFGF and the TGF-β superfamily was reported from ...

Growth and destruction are central components of the neuronal injury response. Injured axons that are capable of repair, including axons in the mammalian peripheral nervous system and in many ...

Neurons within the central nervous system lack the intrinsic capacity to regenerate their axons after injury, leading to permanent functional deficits. In contrast, peripheral sensory neurons with ...

Microglia continuously monitor synapses, but active synaptic remodeling by microglia in mature healthy brains is rarely directly observed. We performed targeted photoablation of single synapses in ...