And, not surprisingly, it did: fatty acyl-CoA synthetase. This is an enzyme that plays a key role in fat metabolism, creating an intermediary that allows cells to add more carbons onto growing ...

Scientists from CSIR-Central Drug Research Institute have discovered that targeting the enzyme acyl-CoA synthetase 4 (ACSL4) can help treat triple negative breast cancer (TNBC), which lacks ...

Acyl carrier protein (ACP) plays a central role in fatty acid biosynthesis, acting as a molecular "shuttle" that carries, ...

Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is a genetic condition that prevents the body from breaking down fat stores for energy. It can be fatal without early diagnosis and treatment.

LX9851, discovered and developed by Lexicon, is a potent and selective oral small molecule inhibitor of Acyl-CoA Synthetase 5 (ACSL5) . ACSL5 plays a key role in the metabolic pathway ...

Lexicon’s drug is an oral small molecule that blocks Acyl-CoA Synthetase 5, or ACSL5, a metabolic pathway that’s thought to be involved in energy expenditure and fat accumulation.

LX9851, discovered and developed by Lexicon, is a potent and selective oral small molecule inhibitor of Acyl-CoA Synthetase 5 (ACSL5) . ACSL5 plays a key role in the metabolic pathway which ...

Comparatively, in the genus Acremonium, isopenicillin N is converted into penicillin N via a two-enzyme system that involves both acyl-CoA-synthetase and acyl-CoA-racemase. The genes for beta ...

As companies continually search for next-generation obesity prospects, one of the leaders in the disease space, Novo Nordisk A/S, has obtained an exclusive license to a preclinical-stage, ...