Twin and genetic studies have underscored the heritability of circulating 25 (OH)D levels (estimated to be between 23% and 77%), and recent genome wide association studies have identified several ...

The Vitamin D–antimicrobial Peptide Pathway and Its Role in Protection against Infection Adrian F Gombart Disclosures Future Microbiol. 2009;4 (9):1151-1165. ... Cathelicidins, Defensins ...

Magnesium is essential for vitamin D metabolism and activation in the body. Insufficient magnesium levels can impair the conversion of vitamin D into its active form, leading to reduced ...

Genetic variation in vitamin D receptor (VDR) binding is associated with a patient’s susceptibility to multiple sclerosis (MS), according to a study recently published in PNAS.

Objective: Vitamin D and thyroid hormones have crucial roles in bone metabolism. This study aims to explore the effects of vitamin D on bone metabolism in mice with thyrotoxicosis and its mechanisms.

Notably, these benefits were associated with vitamin D’s suppression of the renin-angiotensin system (RAS), whose chronic activation promotes the production of pro-fibrotic molecules and the ...

Patient’s condition Vitamin D may reduce the need for patients to be put on a ventilator to help them breathe, but the evidence is uncertain. One study (in participants with severe COVID-19) reported ...

Expression of Vitamin D regulated genes in COVID19 patients. a) Number of genes found overlapped with Vitamin D regulated genes and three SARS-COV-2 datasets are denoted. b) 43 genes were ...

Figure 1. Vitamin D signaling in neurons reduces microglial activation. (A) N2a cells were differentiated into neuronal-like cells using retinoic acid, treated with calcitriol (0–1,000 nM), and the ...