Valproic acid (VPA), formally 2-propylpentanoic acid, is a low–molecular weight branched-chain fatty acid. It is a derivative of valeric (pentanoic) acid1, which occurs naturally in valerian ...

The antiepileptic drug valproic acid (VPA) has been shown to influence the neural differentiation and neurite outgrowth of neural stem cells. Sympathoadrenal progenitor cells share properties with ...

Valproic acid dissociates to form valproate ions in the body, which has numerous effects on the neuronal tissue in the brain. This accounts for its broad clinical activity and use in several ...

Valproic acid first hit the market in the 1960s as an anticonvulsant medication, but by the 1980s, the drug's link to birth defects became apparent, according to BBC News.

Valproic acid has been shown to exert neuroprotective effects and promote neurite outgrowth ... Changchun 130033, Jilin Province, China; 2 Key Laboratory of Molecular Epigenetics of Ministry ...

Valproic acid is widely used to treat various types of seizure disorders, but to this point, the cellular mechanism affected by its anticonvulsant properties were not well understood.

Exposure to valproic acid monotherapy was recorded for a total of 180 registrations, with 122 registrations in the case group, 45 in control group 1, and 13 in control group 2.

Valproic Acid: A Happy Accident, Again? A recent study suggested that patients with glioblastoma treated with radiation and temozolomide lived a few months longer if they were taking valproic acid ...

Dr. Laurie Barclay discusses a new study investigating the risk for congenital malformations in children of mothers exposed to valproic acid during the first trimester of pregnancy.

Valproic acid is one of the most widely prescribed drugs for the treatment of epilepsy. It has also been shown to be effective for the treatment of mood disorders and migraine headaches.

Valproic acid (VPA) is an approved treatment for epilepsy, bipolar disorder, ... 4D Molecular Therapeutics and Second Sight Medical Products outside the submitted work.