Valproic acid 激活 Notch1 信号并抑制小细胞肺癌 (SCLC) 细胞的增殖。Valproic acid 可用于癫痫、双相情感障碍和偏头痛等的研究。Valproic acid 通过上调 BNIP3 诱导自噬和线粒体自噬，并通过上调 PGC-1α 来诱导线粒体的生物合成。 英文别名：2-Propylpentanoic Acid; VPA ...

Valproic acid (VP) is a very effective therapy for the management of generalized epilepsy. However, its use during pregnancy leads to increased risk of teratogenesis and cognitive malfunctioning in ...

Prenatal uptake of valproic acid (VPA) was associated with increased risk of fetal cardiac anomalies and autism spectrum disorder (ASD), but uptake of VPA is considered the only effective treatment ...

Valproic Acid(Depakene) generic is an anticonvulsant, ... (FAS) is a group of physical and mental defects that occur in the fetus due to alcohol consumption by the mother during pregnancy.

Background: A rodent autism spectrum disorder (ASD) model based on prenatal exposure to valproic acid (VPA) is widely recognized as a prominent model. Social behavior in rodent ASD models has ...

The researchers found that among patients using valproic acid, pregnancy rates remained stable over time. Across all indications, the pregnancy incidence rate was 1.74 (95% CI, 1.14-2.53) per 100 ...

Valproic acid is a widely-used type of seizure medication available in a variety of brand names. ... In another group, over 80% of people with new tonic-clonic seizures and related types didn't have ...