Gilead Sciences hits a 52-week high buoyed by investor optimism. We believe there is still room for growth and recommend the ...
A new study finds that ursodeoxycholic acid (UDCA) effectively dissolves gallstones in 60% of patients after sleeve ...
对此,Shilpa Medicare的董事总经理Vishnukant Bhutada表示:“我们对SEC的批准感到非常高兴,并期待尽快获得市场授权。我们致力于与监管机构紧密合作,尽快将这一创新疗法带给患者,计划在即将到来的财年内在印度上市。” ...
Shilpa Medicare Limited (BSE: 530549) (NSE: SHILPAMED), a leading API and formulation manufacturer, announces that the ...
研究人员运用了多种关键技术方法。在纳米囊泡制备方面,通过超声破碎 RAW264.7 细胞,再经一系列处理得到巨噬细胞来源的纳米囊泡(NVs),并将 UDCA 载入其中,进一步修饰得到线粒体靶向的纳米囊泡(UDCA-NVs-TPP) 。在细胞和动物实验中,利用多种细胞模型和 PD 小鼠模型,借助 CCK-8、ABTS ...
根据美国食品药品管理局(FDA)发布的安全警告,患有无肝硬化的原发性胆汁性胆管炎(PBC)的患者使用Ocaliva® (奥贝胆酸)治疗时报告了严重的肝损伤。 Ocaliva 是一种法呢醇 X 受体激动剂,于 2016 年获得加速批准用于治疗 ...
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吉利德再添肝病新药
近日,吉利德宣布,欧盟委员会(EC)已有条件批准Seladelpar上市,与熊去氧胆酸(UDCA)联用,治疗对UDCA单药应答不足的原发性胆汁性胆管炎(PBC)患者;或者作为单药,治疗对UDCA治疗不耐受的PBC患者。
Hepatocellular DILI is characterized by inflammation, necrosis, and apoptosis, while cholestatic DILI involves bile plug formation and bile duct paucity. Ursodeoxycholic acid (UDCA), a widely used ...
Ursodeoxycholic acid (UDCA) is the therapeutic agent most widely used for the treatment of cholestatic hepatopathies of diverse etiologies and has been mainly used as a supportive treatment in ...
ALF-agreement, Forte, FORMAS, Swedish Heart Lung Foundation, SciLifeLab / Knut and Alice Wallenbergs Foundation, Swedish Research Council, Swedish Social Insurance Agency SCIFI-PEARL is a nationwide ...
The European Commission also granted conditional marketing authorization for seladelpar for the treatment of primary biliary cholangitis in combination with ursodeoxycholic acid (UDCA) in adults ...