Prostate cancer is one of the most common cancers diagnosed in men and is typically monitored through prostate-specific antigen (PSA) levels. Metastatic prostate cancer usually presents with elevated ...

Alloimmune responses in particular may facilitate the induction of autoimmune responses to self-antigens and these can then collectively lead to chronic rejection. Both ColV and Kα1T are ...

School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, No. 66, Gongchang Road, Guangming District, Shenzhen, Guangdong 518107, China ...

Neoantigen vaccine is a promising breakthrough in tumor immunotherapy. However, the application of this highly personalized strategy in the treatment of solid tumors is hindered by several obstacles, ...

Florham Park, NJ, United States Cellular senescence, a state of stable cell cycle arrest, acts as a double-edged sword in cancer biology. In young organisms ... Dendritic cells present ...

For many decades, the foundations of cancer treatment have been surgery, chemotherapy, and radiation therapy. But, in recent years, a newer therapy in the form of immunotherapy has emerged, ...

That's what happened when I came across heat shock proteins. I was a postdoc at Sloan Kettering in 1985, and I had just received the results of the N-terminal sequence of gp96, a tumor-rejection ...

A major obstacle in cancer treatment is the persistent resistance of cancer cells to a variety of therapeutic modalities. The tumor microenvironment (TME) which includes encompasses all non-malignant ...