CAR-T cells, which are genetically programmed to specifically recognize and kill target cells, have altered the therapeutic landscape of lymphoma. After the tumor antigens are identified by scFv, ...

Finally, CD8 + T cell-mediated antitumor immunity to promote immune escape was suppressed. Wondering whether blockade of the ...

Cancer plasticity allows tumor cells to change their identity, evade therapies, and adapt to environmental pressures, contributing to treatment resistance and metastasis. New research is targeting ...

Karin Pelka is the 2025 recipient of the AAAS Martin and Rose Wachtel Cancer Research Award for her work with these critical ...

Our immune system is constantly monitoring our body. In order to survive, cancer cells need to evade this surveillance. Now a new study by researchers at the Netherlands Cancer Institute reveals a ...

Immunotherapy is based on harnessing a person’s own immune system to attack cancer cells. However, patients with certain tumors do not respond to these therapies and it remains unclear why.

By Gina Kolata In a surprise discovery, researchers found that cells from some types of cancers escaped destruction by the immune system by hiding inside other cancer cells. The finding ...

Once the immune cells engulf the tumor, the toxin is released inside, becoming activated and creating pathways that allow tumor DNA and protein fragments, which are usually destroyed, to escape.

Drug resistance in solid tumors remains a major obstacle in oncology, frequently leading to treatment failure and disease relapse. A central contributor to ...

Most bacteria living in the human body help us thrive, but recent studies show that some infiltrate tumors, helping them grow, spread, and become more difficult for the immune system to destroy.