近年来，mRNA肿瘤疫苗在癌症治疗领域方面展现出巨大潜力，并取得了显著进展，但仍然面临递送、免疫反应调控、规模化生产等许多挑战，距离全面用于临床治疗仍需大量研究和系统性验证。不过，随着基础研究的深入和相关技术的进步，mRNA肿瘤疗法有望在未来几年取得 ...

Both prophylactic vaccines and therapeutic vaccines are being developed against cancer. An example of the ... They appear to have very different target antigens and each of these cancers is ...

For example, T-cell engagers (TCEs) are bsAbs designed to simultaneously bind CD3 on T cells and a tumor-associated antigen (TAA) on cancer cells, bringing the T cell and cancer cell into close ...

Republicans suggest eliminating TSA with idea already used at SFO Monumental Ruins Emerge Following Massive Myanmar Earthquake Garth Brooks found Nashville 'gutted' after returning to country ...

School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, No. 66, Gongchang Road, Guangming District, Shenzhen, Guangdong 518107, China ...

Most tumor cells express certain tumor-specific or tumor-associated antigens (TSA or TAA). By combining the “antigen recognition domain (scFv)” of antibodies that recognize these tumor antigens with ...

a biotechnology company developing engineered immunoglobulin A (IgA) antibodies, to create the world’s leading pan-isotype cancer antibody company. As a result of the combination of these two ...

Data from a Phase I trial found it to be safe and well tolerated with early signs of clinical activity EPS 401 (formerly TIGA-001), an anti-EGFR IgA antibody with IND-enabling studies underway Further ...

Combined clinical-stage company benefits from a strong pipeline: MOv18 IgE, an anti-Folate Receptorα IgE antibody, currently in a Phase Ib Proof of Concept trial in platinum-resistant ovarian cancer.

called antigen-presenting extracellular vesicles (AP-EVs), that activate immune cells inside tumors. These AP-EVs carry key immune-boosting signals, helping T cells—the body's natural cancer ...

APC, Antigen Presenting Cells, which could be Neutrophils, Dendritic cells, or monocytes/macrophages. Figure prepared using BioRender. Increased tumor infiltration of neutrophils, often accompanied by ...