(2) These cells are activated using anti-CD3/CD28 antibodies to stimulate their proliferation. (3) Genetic modification of the T cells is performed by inserting the CAR gene, enabling them to ...

ABINGTON TWP, Pennsylvania -- 'Project Chemo Crochet is the initiative bringing warm blankets to patients in cancer treatment. Rather than having a team of only local volunteers, their ...

recognizes specific tumor antigens through its chimeric antigen receptor (CAR), leading to enhanced phagocytosis of the tumor cells and concomitant presentation of tumor antigen to T cells for their ...

Antigen recognition plays a key role in both the innate and adaptive immune systems. Antigens are small molecular components of cells or non-cellular biological materials. Most often, they are parts ...

The immune stimulatory effects of radiotherapy can be exploited by concurrent PI3Kγ inhibition to significantly constrain pancreatic cancer growth. Combined radiotherapy and PI3Kγ inhibition stimulate ...

High levels of the cancer antigen 15-3 (CA 15-3) can indicate that breast cancer is present or has spread to other parts of the body. Among other things, the CA 15-3 blood test can reflect how ...

Leveraging their unique structural attributes and facile modification capabilities, VLPs can serve as an effective platform for the delivery of tumor antigens, thereby stimulating the immune system ...

From published reports, a prioritized list ranking 75 tumor-associated vaccine antigens by these criteria is presented. Given the large number of potential tumor vaccine antigens, and the general ...

1Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut. 2Department of Genetics, Yale University School of Medicine, New Haven, Connecticut.

Biologic characterization of these latter antigens is based principally upon testing the antibodies produced in tumor-bearing hosts against the antigens of tumor cells. Another distinction may be made ...