These vesicles effectively downregulate PD-L1 on tumor cells, transforming them from a dormant to an active ... involved in immune regulation. They also transport miR-511-3p, a macrophage-specific ...

Department of Nutrition, Case Western Reserve University, Cleveland, Ohio 44106, United States Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska 68583, ...

In this context, Extracellular Vesicles (EVs) present a promising alternative ... Exosomes can be released by cells: a) carry new viral particles, which contributes to viral dissemination; b) ...

Most nuclear and cytoplasmic functions of the NPC seem to increase the efficiency and integration of transport into the broader milieu of the cell. Although the nuclear pore complex (NPC ...

Increasing our understanding of the function of ABC and RND transporters in mammalian cells and their involvement in lipid transport and homeostasis should reveal the mechanisms of subcellular ...

Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States Sickle cell disease (SCD) is a devastating hemolytic disease, ...

Taiwan International Graduate Program in Molecular Medicine, National Yang Ming Chiao Tung University and Academia Sinica, Taipei 11529, Taiwan Graduate Institute of Nanomedicine and Medical ...

Presence of UDP-glucose:glycoprotein glucosyltransferase (UGGT) and α1,2-mannosidases as endoplasmic reticulum protein quality control (ERQC) components in Cryptococcus neoformans.

Fuel cells that react liquid sodium metal with air could be the power source required to give electric airplanes much longer ranges, a new paper has proposed. The idea has yet to leave the ...

Japan’s synthetic blood is universal, shelf-stable, and may redefine emergency medicine by 2030. Here’s why it matters.