Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...

This article explores how cancer biomarkers improve early detection, guide treatments and predict outcomes to transform ...

Pharmacogenomics. 2013;14(3):15-24. Two approaches are commonly used in PGx discovery research: the candidate gene approach and genome-wide studies. The candidate gene approach focuses on one or a ...

Scientists in Australia have uncovered a new way cancer may begin in the body—through tiny circular pieces of genetic ...

Genes and Genetics News. ... May 29, 2025 — Mutations accumulated in mitochondrial DNA associated with aging were earlier believed to cause aging by decreasing the energy-producing function ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

MECP2 MUTATIONS IN RS AND OTHER CLINICAL PHENOTYPES. The MECP2 gene is located at q28 on the human X chromosome, and has been demonstrated to undergo X inactivation in mice and humans. 28, 29 It ...

Sex Chromosome Inheritance . Sex chromosomes are the X and Y chromosomes that play a role in gender differentiation. Females inherit two X chromosomes, one from each parent. So a female can have a ...

Revise mutations Revise single gene, point, frame-shift and chromosome structure mutations and their causes for you Higher Human Biology exam. Higher Human Biology - Mutations. revision-guide ...

Barth syndrome, which primarily affects boys due to its X chromosome mutation pathogenesis, causes heart problems, muscle weakness, and immune system issues. There are currently no FDA-approved ...