with DNA actively facilitating interactions between various transcription factors. 1 With the regulatory code being far more complex than the genetic code, which explains how DNA sequence determines ...

While these tools can predict the overall structure, they often cannot look into smaller details, such as how transcription factors interact with each other on DNA. These small interactions can ...

with DNA actively facilitating interactions between various transcription factors. 1 With the regulatory code being far more complex than the genetic code, which explains how DNA sequence determines ...

Collaborative research led by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center defines a novel approach to understanding how certain proteins called transcription ...

This standard oscillator refers to the transcriptional translation feedback loop (TTFL). Two transcription factors named circadian locomotor output cycles kaput (CLOCK) and brain and muscle ARNT-like ...

Transcription factors, proteins that act as master regulators of gene expression, play a critical role in cancer development. Despite years of effort, designing small-molecule drugs to block these ...

Contributed by Jian-Kang Zhu; received November 8, 2024; accepted March 7, 2025; reviewed by Cao Xu and Ramin Yadegari ...

The latest insights into transcription factors provide a deeper understanding of the disease's progression and potential therapeutic interventions. Transcription factors are critical proteins that ...

Under normal circumstances, the dominant mouse would usually step forward while the subordinate mouse would retreat. “But when we put in our synthetic transcription factor, all bets were off, and the ...

Any debt capital is offset by a debt liability on the balance sheet. The capital structure of a company determines what mix of these types of capital it uses to fund its business. Economists look ...