High uric acid, a common concern due to modern lifestyles, can lead to gout and kidney stones. The body signals its presence through joint pain, stiffness, fatigue, and changes in urine. Small, ...

A swollen toe is a key sign of gout, a type of arthritis. But your ankle is at risk too. Here's what gout symptoms in an ankle look like and the treatments that you can try.

I suffer from Gout and a day has not gone past since my 26th birthday that I have not had it in a joint somewhere. I have tried Puricos & Allomaron with no success. I have now developed Tophi on my ...

Background Although typically a late feature of gout, tophi may present early in the course of disease. The aim of this study was to identify factors associated with the presence of early ...

Background: Gout is a common disease; however, a gout tophus occurring within the spinal dura is exceedingly rare, with only two cases reported to date. Case presentation: We report the case of a ...

These decrements in HRQOL vary across the spectrum of clinical phenotypes according to the presence and frequency of gout symptoms and signs. Patients with confirmed tophi and more frequent acute ...

Objective To investigate the effect of intensive lowering of serum uric acid (SUA) levels by pegloticase on the resolution of tophi in patients with refractory gout. Methods Descriptive study in ...

This process of NETosis is critical for understanding tophaceous gout, since tophi are composed of NETs and densely packed MSU crystals. Purine metabolism in apes and humans is fundamentally different ...

Tophi are firm, painless yellow lesions that form in and around the joints in people with advanced gout. They have a uric acid (monosodium urate) core, and the skin that covers them can become ...

Tophi. The crystals that cause your ... your health and keep your joints healthy, but start back gradually after a flare. How long can gout symptoms last? Gout flares don't usually last more ...

Bone erosion in patients with gout and tophi was associated with tophi duration, drinking history, ulceration, and serum creatinine levels. Bone erosion in patients with gout and tophi was ...

Bone erosion in patients with gout and tophi was associated with tophi duration, drinking history, ulceration, and serum creatinine levels. Bone erosion in patients with gout and tophi was associated ...