A study co-led by Premiexplored how nitrosylation, a modification caused by nitric oxide, affects the cancer-promoting MEK/ERK pathway and a process called immunogenic cell death in NRAS-mutant ...

Nitrosative stress impairs coronary collateral circulation during metabolic stress. It induces iNOS-mediated AMPK S-nitrosylation to disrupt VSMC reprogramming. Nitrosative stress is a novel mechanism ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Thiol antioxidant dithiothreitol (DTT) is used ...

Upon inflammation and changes in the cellular microenvironment, many extracellular soluble and membrane proteins undergo thiol modifications, particularly dithiol–disulfide exchange, ...

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Find more information on the Altmetric Attention Score and how the score is calculated. Thiol-maleimide and thiol-vinylsulfone cross-linked hydrogels are widely used systems in 3D culture models, in ...

S-nitrosylation, a phylogenetically conserved posttranslational modification of proteins that mediates transduction across a broad spectrum of cellular signaling pathways, involves the covalent ...

Coenzyme A (CoA) is a small-molecular-weight thiol that plays a central role in cellular metabolism. We have discovered a novel, phylogenetically conserved class of enzymes that reduce S-nitroso-CoA ...

Keywords: S-nitrosylation, thiol pool, nitric oxide signaling, cold stress. Citation: Sehrawat A, Abat JK and Deswal R (2013) RuBisCO depletion improved proteome coverage of cold responsive ...

Find more information on the Altmetric Attention Score and how the score is calculated. Various pathways to bioconjugates based on thiol chemistry are discussed. Thiol-halogeno, thiol-parafluoro, ...