Scientists from the Institute of Applied Ecology of the Chinese Academy of Sciences have discovered a promising new use for a key intermediate in vitamin C production, demonstrating its potential ...

Thiamine diphosphate reduction strongly correlates with brain glucose hypometabolism in Alzheimer’s disease, whereas amyloid deposition does not. Alzheimer's Research & Therapy 2018, 10 (1) DOI: ...

Thiamin pyrophosphate is a required cofactor in all organisms. The biosynthesis of thiamin requires the independently synthesized 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate (HMP-PP) and ...

A comprehensive literature search was conducted from July 2023 to April 2024. Clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human participants were identified ...