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it is conceivable that TRAIL is differentially expressed in Th1 and Th2 cells. Since Th1 cells are sensitive to TRAIL- and CD95L-induced apoptosis, these cells could be the targets of TRAIL- or ...
为了揭开这些谜题,来自加利福尼亚大学欧文分校的研究人员在《Cell Stem Cell ... 诱导强烈的 Th1 细胞分化,并且在培养期剩余时间内保持较高水平,还能引发更高频率的记忆 CD8 细胞;而非活抗原(IIVs 和亚单位疫苗)刺激的 T 细胞则主要呈现 Th2 表型。
Effects of mangiferin on cell proliferation 研究发现芒果苷对静息态淋巴细胞无毒性,但能浓度依赖性地抑制PHA诱导的增殖。100 μM芒果苷的抑制效果与地塞米松相当,证实其免疫抑制潜力。 该研究首次证实芒果苷能特异性调节人类淋巴细胞功能,其双重抑制Th1/Th2但不 ...
这种多重ELISA试剂盒用于Th1/Th2/Th17细胞因子,旨在半定量和同时测定与T辅助细胞分化相关的细胞因子。该试剂盒同时测定干扰 ...
1 Th1 cells primarily produce interferon (IFN)-g and interleukin (IL)-2, whereas Th2 cells produce IL-4, IL-5, IL-6, IL-10, and IL-13. The two helper T cell classes also differ by the type of immune ...
Like Th1 and Th2 cells, Th17 cells produce a group of distinctive cytokines — interleukin-17 (also called interleukin-17A), interleukin-17F, interleukin-22, and interleukin-21 — all of which ...
these cells can differentiate into either TH1 cells, which fight against viruses and intracellular pathogens, or TH2 cells, ...
It has been challenging to create T cells that are both potent and durable. In a new study, researchers report the potent anti-tumor properties of hybrid Th1/Th17 cells that combine the cancer ...
On antigen presentation, naive T cells are subjected to either interleukin-12 and interleukin-18 or interleukin-4, which polarizes them to Th1 or Th2 helper cells, respectively. Th1 cells produce ...
The result was a hybrid Th1/17 T cell that has the best anti-cancer characteristics of both parent cells. "We've known about how T cells can fight tumors for more than three decades. However ...
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