TNF down-regulates insulin-induced activation of mitogenic signal pathways in Kym-1 cells. Recently, a negative regulatory crosstalk between insulin and TNF signaling cascades has been identified ...

Tuesday, June 3, 2025. News & Perspective Drugs & Diseases CME & Education Video Decision Point Drugs & Diseases CME & Education Video Decision Point ...

Crosstalk between PGE2 and TNF signaling and its regulation by IFN-γ. (A) PGE2 costimulates TNF-induced expression of select inflammatory genes such as IL-1 and Notch pathway genes and neutrophil ...

Polysaccharides from Black Mulberry Attenuate Colitis through Gut Microbiota Mediated TNF-α/pNF-κB/ICAM-1 Signaling Pathway. Click to copy article link Article link copied! Li-Tao Yi * Li-Tao Yi.

A rare case of adalimumab-induced pustular psoriasis in a hidradenitis suppurativa patient was successfully treated with ...

Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain ...

This article explores the complex roles of cytokine networks in the development and progression of autoimmune diseases.

Keratinocyte Arginase1 promotes wound closure by modulating inflammatory signals and lipocalin-2, revealing a therapeutic ...

Up to half of patients with Crohn's disease, an inflammatory bowel disease, develop a complication called fibrosis, where the ...

Ruxolitinib, a selective inhibitor of Janus kinase 1 and 2, has emerged as a pivotal therapeutic agent in the management of myeloproliferative neoplasms, particularly primary myelofibrosis. The ...