This article explores the complex roles of cytokine networks in the development and progression of autoimmune diseases.

Corbus Pharmaceuticals Holdings' financial position is stable for now, with about two years of cash runway. Click here to ...

Follistatin-344 (FS-344), a glycoprotein variant, has emerged as a focal point in scientific research due to its potential ...

Photodynamic therapy (PDT) resistance limits treatment efficacy in oral leukoplakia (OLK). This study identifies p-NRF2 as a ...

Concludes Strategic Alternatives Review and Provides Update on Development of KER-065LEXINGTON, Mass., June 09, 2025 (GLOBE ...

Keros Therapeutics, Inc. (“Keros”) (Nasdaq: KROS), a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapeutics to treat a wide range of patients with ...

TGF-beta signaling also controls vascular development, with loss-of-function mutations in TGF-beta receptor 1 (TGFBR1/ALK5), TGFBR2, the EC accessory receptor Endoglin, or various SMADs producing ...

Endothelial cell-specific loss of TGF-beta signaling in mice leads to CNS vascular defects, specifically impairing retinal development and promoting immune cell infiltration. The data are solid, ...

For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once ...

Why context is key for TGF-Beta's role in cancer metastasis. The study brings together two longstanding areas of research for the Massagué Lab: TGF-beta signaling and metastasis.