RNA-seq and spatial transcriptomics showed immune cell subsets that drive kidney and lung complications in systemic sclerosis patients.

At the start of the COVID-19 pandemic, information began to trickle in about who was at higher risk of a dangerous outcome from infection: men, those over 65, smokers, those with obesity. It turns out ...

A new platform comprehensively profiles CAR T-cells during manufacturing, revealing phenotypic shifts. This allows for ...

T cells are the immune system’s frontline fighters. When they detect danger, they rapidly multiply and transform into effector cells that destroy pathogens.

γδT cells represent a unique and versatile subset of T cells characterized by the expression of T-cell receptors (TCRs) composed of γ and δ chains. Unlike conventional αβT cells, γδT cells do not ...

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies. T cell-based ...

It is not clear whether this conclusion applies to other T cell subsets. Here, we investigated the role of TCR characteristics in the fate choice of evolutionarily conserved innate-like T cells. We ...

cells and regulatory T-cells (Tregs). However, current paradigms are rapidly evolving as new technologies to study immune cell subsets in the skin have been advanced. For example, recently minted ...

Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases. As they work to shed light on ...

Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases. As they work to shed light on ...

Scientists and clinicians at University College London (UCL) and Great Ormond Street Hospital (GOSH) have discovered a small subset of T-cells that may play a key role in whether chimeric antigen ...