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Xie Zhen's team from Tsinghua University published a research article titled "SPECIFIC: A systematic framework for ...
Next, we demonstrate that, in a single design cycle, it is possible to create functional, purely synthetic yeast promoters that achieve substantial expression levels (within the top sixth ...
题目:Design of synthetic promoters for cyanobacteria with generative deep-learning model 期刊:Nucleic Acids Research 影响因子:19.16 发表时间:2023.5.29 原文作者 ...
Chromatin Bioscience, a leader in the design of synthetic promoters and gene control systems, announced a collaboration agreement with Astellas Pharma, a global life sciences company. Under the ...
LONDON – Synthetic promoters – a new and controllable means of directing gene expression – are starting to be deployed to increase the potency and specificity of gene therapies and to boost yields in ...
6 个月
AZoLifeSciences on MSNEngineering Yeast Promoters for Biologic ManufacturingIn a paper now published in the journal Nature Communications, they describe three design principles for yeast ...
The molecules produced include important therapeutic proteins that can be expressed in a plant by altering its synthetic switches or metabolic pathways. Genetic elements like DNA promoters and ...
ESO-T01 is the first in vivo B-cell maturation antigen (BCMA) CAR-T candidate to reach the clinical stage and utilises a synthetic promoter designed using Chromatin Bio’s proprietary promoter design ...
ESO-T01 is the first in vivo B-cell maturation antigen (BCMA) CAR-T candidate to reach the clinical stage and utilises a synthetic promoter designed using Chromatin Bio's proprietary promoter ...
What we focus on is containment – ensuring the bacteria is only active within the tumor. We achieve this by engineering a biosensor library in the lab. We design synthetic promoters that respond to ...
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