The National Strategy for Gene and Cell-based Therapies Funds the University Hospital Regensburg and the Leibniz Institute for Immunotherapy to Advance Cutting-Edge T Cell Therapy for Sarcoma Patients ...

One of the hardest lessons learned occurred after I inadvertently failed at communication and education before transferring a ...

Sarcomas comprise a heterogenous group of malignancies, of more than 100 different entities, arising from mesenchymal tissue, and accounting for 1% of adult malignancies. Surgery, radiotherapy and ...

The Soft Tissue Sarcoma market is expected to surge due to the disease's increasing prevalence and awareness during the ...

Cell and gene therapies have undergone notable milestones in the last 12 months, with solid tumors and diabetes treatments.

We aimed to investigate their developmental origin and relationship with adult progenitors. Conclusions Our findings blueprint a cell atlas of mouse synovial fibroblasts and progenitors in healthy and ...

Clear cell sarcoma (CCS), or malignant melanoma of soft parts, is a rare, extremely aggressive soft tissue sarcoma, which accounts for less than 1% of soft tissue sarcomas. Though extremely rare, CCS ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

Little is known about discrete cell types and molecular mechanisms in PTOA synovium. We aimed to describe synovial cell populations and their dynamics in PTOA, with a focus on fibroblasts. We also ...

Cancer immunotherapy is shifting paradigms in cancer care. T cells are an indispensable component of an effective antitumor immunity and durable clinical responses. However, the complexity of the ...