Integral membrane protein structure determination traditionally requires extraction from cell membranes using detergents or polymers ... and cofactors that are essential to biological function. Very ...

In biology classes from high school through university, I learned that mitochondria are little objects that reside within ...

New research challenges the view that proteins are the only key to evolution, highlighting the importance of lipids.

Personalised medicine is already a reality in clinical practice, and CAR-T cell therapy is one of its most promising tools.

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which ...

Researchers have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization. This is ...

The fungus also forms a plant-derived structure called ... inability to nail down the function of Ppe1 likely stems from two underlying assumptions with weak support. Firstly, the authors assume that ...

Here we report that the endoplasmic reticulum (ER)-resident SNARE Sec22b has a conserved non-fusogenic function in plasma membrane expansion ... or transfected COS7 cells were homogenized in ...

My search for answers to these stupendously ambitious questions led me, it now seems inexorably, to mitochondria. This idea of mitochondria being little batteries with a built-in charger, about as ...

Membrane biophysics is the study of the ... they have on paracellular transport and phenomena relating to cell shape. An improved structure of the TRPV3 pentamer, together with molecular dynamics ...

Knockdowns of Spigot orthologs in worms, flies, and human cells produced consistent disruptions in membrane-related functions. The revealed LPD-3 structure provides a foundation for further ...