CMD-GEN is a structure-based framework for selective inhibitor design, combining coarsegrained pharmacophore sampling with generative models to optimize molecular stability, druglikeness ...

The starting point for all structure-based design work, whether ligand or protein based, is the choice of a suitable target. Antimicrobial-drug targets should be essential, have a unique function ...

Explore innovative architecture that harmonizes with nature, transforming urban landscapes into serene, green spaces for all.

Nature Structural & Molecular Biology is an academic journal publishing research articles, reviews, news and commentaries in structural biology and molecular biology, with an emphasis on papers ...

2008: Scientists Gamify Protein Folding and Design Baker literally made Rosetta ... Access to these protein structures opened the door to a deeper understanding of their functions and potential ...

Biophysicists have elucidated why unexpected structures can sometimes arise during protein design. Artificially designed proteins are usually based on building blocks that obey strict rules of ...

A fundamental understanding of photosynthesis in nature is crucial for applied photosynthesis, which may well prove to play a key role in overcoming some of the greatest challenges that humankind is ...