A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

RAD52 has already shown promise as a drug target. Inhibitors of the protein can selectively kill cancerous cells while ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

A research group led by Gian Gaetano Tartaglia, Principal Investigator at the Italian Institute of Technology (IIT), ...

That includes DNA, RNA, antibodies, the ligands that bind to receptors in cells, and more – an ... accuracy for the prediction of 3D protein structures, it offers a big increase for antibody ...

As basic building blocks of cells, proteins have vital functions in the organism ... among them cancer as well genetic and neurodegenerative diseases,” explains Ed Hurt. Along with the structural ...

By investigating how lipid-soluble Cer is transported between cells, the researchers demonstrated that high-density lipoprotein (HDL) serves as the primary carrier for Cer transport. Upon reaching ...

Harvard Medical School scientists have identified a key protein in the human immune system that drives inflammatory and ...

"We discovered that abnormal tau proteins accumulate in retinal ganglion cells, which are key nerve cells in the eye that send information to the brain," said Maya Koronyo-Hamaoui, Ph.D ...