Company to showcase preclinical studies of ARV-393, an investigational oral PROTAC BCL6 degrader, as a single agent in models ...

funded by the NIH’s Somatic Cell Genome Editing program. This same NIH program connected the IGI researchers with the team at CHOP and the University of Pennsylvania. In August 2024, the team at CHOP ...

The findings suggest that somatic growth deceleration primarily results not from an increase in cell-cycle time but from a decrease in growth fraction (fraction of cells that continue to proliferate).

2 Role of Golgi complex resident proteins in somatic cell division and cell cycle progression The available evidence increasingly points to a role for GC proteins in cell cycle progression. Indeed, ...

With so much at stake, nature keeps it tightly controlled in a process called the cell cycle that scientists thought they thoroughly understood. UCSF scientists discover that multiciliated cells ...

They concluded that psoriasis is not caused by somatic mutations in skin cells. Psoriasis is one of the most common skin conditions in the United States. Mediated by the immune system, it causes ...

Here, we found that the incubation of mouse sperm with hamster fibroblasts or human epithelial cells in culture induces the fusion between these somatic cells and the formation of syncytia, a pattern ...

Checkpoint kinase 1 (CHK1) is a protein kinase that regulates cell cycle progression in somatic cells. Here, we show that CHK1 regulates cell cycle progression in early mouse embryos by restraining ...

Walsh is senior author of the team’s published paper in Cell Genomics, titled “Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 ...

State Key Laboratory of Crop Biology, College of Life Science, Shandong Agricultural University, Tai’an, Shandong, China Somatic cell reprogramming (SCR) is the conversion of differentiated somatic ...