In the coming years, senolytic drugs are anticipated to get major traction as research discovers their potential to target age-related diseases and enhance healthspan. With growing investments in ...
Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.
The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.
The study is based on the analysis of human senescent cells in a specific tumor model — melanoma, which affects skin cells known as melanocytes — and, more specifically, melanocytes exposed to ...