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腾讯网
23 天
肝细胞癌治疗新策略:鼓楼医院江春平团队揭示SENP3抑制与抗PD-1免疫 ...
【导读】SUMOylation在肿瘤发生过程中的重要性已受到越来越多的关注,针对这一途径的治疗药物研究也取得了进展。然而,SUMOylation在肝细胞癌 ...
eLife
7 个月
Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage ...
Here we address this question by examining regulatory elements of Srs2, including its phosphorylation, sumoylation, and protein-interaction sites. Our genetic analyses and checkpoint level assessment ...
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