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JAK/STAT 通路:非 HIV 相关隐球菌脑膜炎后炎症综合征治疗的新希望
研究结论和讨论部分进一步强调了这些发现的重要意义。JAK/STAT 通路的激活促进了神经炎症的发生,鲁索替尼能够有效抑制该通路,减轻炎症反应,改善患者的临床症状和生活质量。这不仅为 cPIIRS 的治疗提供了新的方向,也为其他中枢神经系统(central nervous system,CNS)炎症性疾病的治疗提供了宝贵的借鉴。
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