As our bodies grow, cells proliferate to form tissues, and cells frequently have to be repaired or replaced throughout life..

研究人员探究肝细胞衰老与肝癌（HCC）关联及西罗莫司作用，发现二者相关且西罗莫司或可预防 HCC。 在人体的微观世界里，肝脏如同一个繁忙的 “化工厂”，默默承担着众多重要的生理功能。然而，当肝脏遭遇慢性疾病时，就像化工厂的生产线出现了故障，一系列问题接踵而至。在慢性肝病（CLD）的发展过程中，肝细胞衰老这一现象逐渐引起了科学家们的关注。细胞衰老本是细胞的一种稳定且永久的细胞周期停滞状态，其初衷是预 ...

New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...

科学家们通过给小鼠使用一种由癌症研究人员开发的药物来激活p53以抑制肿瘤，从而验证了他们的发现。在老年小鼠中，这种药物并没有减少衰老细胞的数量，而是逆转了标记与年龄相关的SASP的细胞特征，有可能阻止导致炎症衰老的炎症污染。

New research illustrates how a DNA repair protein suppresses senescent cells, reducing age-associated chronic inflammation.

New findings show that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of ...

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery and Interventional Science at University College London has systematically ...