(2) Using gene expression data as input cannot directly establish the relationship between cell types and TCNs in a tissue, making the interpretation of TCNs challenging. (3) Given a cohort of tissue ...

Discovery requirements that were tightened in 2019 were unrealistic. In the years since, prosecutors statewide have expressed continued dismay at valid criminal cases being tossed out ...

In this edition of the biotech bi-weekly, read about the launch of a next-generation PCR kit, the development of a comprehensive functional genomics platform and the unveiling of a cryo-transmission ...

Get Instant Summarized Text (Gist) A new sex hormone, secretoneurin, has been identified as crucial for stimulating ovulation in zebrafish. This neuropeptide, derived from secretogranin-2 ...

The landmark discovery of the BCL-2 gene and its function marked the inhibition of apoptotic cell death as a crucial mechanism driving cancer development. This new review brings together some of ...

Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license ...

College of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China ...

代谢功能障碍相关脂肪肝病（MASLD）是代谢异常引发的慢性肝病，以肝细胞脂质过度蓄积为核心病理特征，伴随内质网（ER）应激、线粒体氧化应激及细胞程序性死亡（凋亡和坏死性凋亡）。RelA（NF-κB p65）和HNF1α是调控脂代谢和ER应激的关键转录因子，二者在 ...

29Developmental Biology and Cancer Department, UCL GOS Institute of Child Health, London, United Kingdom. 32Haematology and Oncology Department, Great Ormond Street Hospital, London, United Kingdom.