The ribosome is a large assembly of proteins and ribosomal RNAs (rRNAs) that functions to translate messenger RNAs (mRNAs) into proteins. The ribosome catalyzes the assembly of amino acids into ...

The ribosome consists of two ribonucleoprotein subunits. The small subunit mediates the interactions between the anticodons of the tRNAs and the codons in the mRNA that they are translating to ...

However, nascent polypeptide products bear an inherent risk of elongation abortion. For example, negatively charged sequences with occasional intermittent prolines, termed intrinsic ribosome ...

Expression of many bacterial genes is regulated by cis- and trans-acting elements in their 5’ upstream regions (URs).Cis-acting regulatory elements in URs include upstream ORFs (uORFs), short ORFs ...

Cells rely on ribosomes to translate genetic messages into proteins, a job that underpins everything from metabolism to growth. Researchers have long believed that when ribosomes encounter an obstacle ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mitochondrial ribosomes are complex molecular ...

Then the cell moves the mRNA from the nucleus to the ribosome, where the mRNA is ‘read’ to make the protein. Sometimes, after the cell copies a recipe to the mRNA, it switches particular ...

Multiuser Center for Biomolecular Innovation, São Paulo State University - UNESP, São José do Rio Preto, SP 15054-000, Brazil Department of Chemistry, Institute of Chemistry, University of São Paulo - ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The gene expression capacity of bacteria depends on the interplay between growth and ...