The researchers used advanced techniques to track ribosome movement and found that the longer the CAG stretch, the more often these traffic jams occurred. This insight shifts the focus from the final ...

Again—how could one missing or unusual protein in the ribosomes cause such a thing? Barna believes that affinity is key. To make a protein, ribosomes don’t receive instructions directly from ...

Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations ...

Ribosomes, the cell's dedicated molecular machines for protein synthesis, make all proteins in life and do so by piecing together one amino acid building block at a time. As they are being ...

Traditionally viewed as a fixed and homogeneous machinery for protein synthesis, the ribosome is increasingly recognized for its heterogeneity, as indicated by emerging studies highlighting the ...

At this stage, a specific protein called GTPBP10 interacts with a long helix of RNA, which is a crucial part of the ribosome. “This helix contains the catalytic center of the ribosome ...

Given their low suppressive efficiency, it has been unclear why miRNAs are equally likely to bind to a CDS. Here, we show that miRNAs transiently stall translating ribosomes, preventing protein ...

Credit: Science (2023). Did you know that every cell in your body has tiny machines called ribosomes? They’re like protein factories, reading the genetic instructions and building the proteins ...