A concise enantioselective total synthesis of 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA), an extremely potent anti-HIV agent, has been accomplished from (R)-glyceraldehyde acetonide in 18% overall ...

J Gastroenterol Hepatol. 2008;23(6):844-855. Assessment of the relationship between anemia and patient baseline characteristics in patients treated with peginterferon-α-2a and ribavirin showed ...

Gemini 2.0 Flash for high-context research synthesis; GPT-4.1 for precise report formatting and editing; Modern React Frontend: Responsive UI with real-time updates, progress tracking, and download ...

Treatments for the condition are limited, although doctors have seen some success with the antiviral drug ribavirin which is used to treat hepatitis C READ MORE: Inside the luxury 794ft superyacht ...

Objective This study aimed to estimate the cost-effectiveness of direct-acting antivirals (DAAs) among patients with non-genotype 1 for the eradication of hepatitis C virus (HCV) infection in ...

Introduction. Although the concept of organic chemistry was proposed before the nineteenth century, the first steps of synthesis analysis took human beings more than 100 years, from 1828, when the ...

Objective We evaluated the efficacy and safety of ledipasvir/sofosbuvir alone and with ribavirin for 8 and 12 weeks in Egyptian patients with and without cirrhosis, who were infected with hepatitis C ...

Background and aim: In this study, we compared the efficacy of triple therapy (interferon alfa, ribavirin, and amantadine) with standard therapy (interferon alfa and ribavirin) in treatment naïve ...

We develop methodology to bridge scenario analysis and risk forecasting, leveraging their respective strengths in policy settings. The methodology, rooted in Bayesian analysis, addresses the ...

The synthesis of new polyhydrides with high superconducting T c is challenging owing to the high pressures and temperatures required. In this study, we used machine-learning potential molecular ...