In animals the compound has been shown to produce an increased renal excretion of sodium, potassium and chloride. 1 However, ... leaving osmotically free water in the tubule for excretion.

Renal Excretion. Approximately 20% of ... Most of the water and electrolytes is then passively or actively reabsorbed into blood from the renal tubules, and are not excreted in the urine. In ...

Almost 10 years ago, a new phosphaturic factor (phosphatonin), FGF-23, was identified in patients with renal phosphate leak. 69,70 Osteoblasts and osteocytes secrete FGF-23, a 251-amino-acid ...

In mice, a consistent phosphorus-rich diet increases phosphate concentration in the proximal tubule fluid of the kidney. Increased phosphate excretion has been associated with tubular damage and ...

The hallmark of the syndrome is increased excretion or loss of certain substances ... "The proximal renal tubules seem to be a specific target of SARS-CoV-2 because of their ACE2 receptors, ...

Each kidney contains approximately 1,000,000 nephrons, which are comprised of a section called the renal corpuscle and the renal tubule. The renal corpuscle is comprised of a network of ...

These transporters control glucose transport and reabsorption in several tissue types, including the proximal renal tubule, small intestine, blood-brain barrier, and peripheral tissues . 13,16 ...

For instance, thiazide diuretics increase re-absorption of calcium in the distal tubules, thereby decreasing urinary calcium excretion; allopurinol, a xanthine oxidase inhibitor, prevents ...

Efficient proximal tubule-on-chip model from hiPSC-derived kidney organoids for functional analysis of renal transporters. iScience , 2024; 27 (9): 110760 DOI: 10.1016/j.isci.2024.110760 Cite This ...

Patel PM, Kandabarow A, Aiwerioghene E, et al. Proton-pump inhibitors are associated with decreased urinary citrate excretion. Presented at: Kidney Week 2020 Reimagined; October 19-25, 2020.