SAN DIEGO, July 1, 2025 /PRNewswire/ -- Arthrosi Therapeutics, Inc., a late-stage biotechnology company developing a potentially best-in-class, highly potent and selective next generation URAT1 ...

Pulmonary rheumatoid nodules can resemble cancer or infection, making biopsy and careful imaging critical for accurate ...

In time, joints can become chronically inflamed and deposits can accumulate in the form of tophi. Gout is one of the most common inflammatory arthritis, affecting up to 1–2% of adult men in western ...

In another study, the evolution of the largest tophi was assessed in 63 tophaceous gouty patients starting urate-lowering therapy. [12] All patients had a complete resolution of their index tophi ...

1. Joint pain and swelling One of the most common signs of high uric acid is sudden joint pain, especially in the big toe. This is known as gout-- which is a form of arthritis that is caused by ...

Khanna, P., et al. (2025) Safety and Tolerability of Pozdeutinurad (AR882) Treatment following Long-term Dosing in Patients with Chronic Gouty Arthritis and Subcutaneous Tophi.

Khanna P, et al. Safety and Tolerability of Pozdeutinurad (AR882) Treatment following Long-term Dosing in Patients with Chronic Gouty Arthritis and Subcutaneous Tophi. Presented at EULAR 2025; OP0300.

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Gout occurs when your body is not able to excrete enough uric acid. When there is too much of this compound in your body, ...

The Phase 2 study of pozdeutinurad (AR882) in patients with tophaceous gout was a six-month 1:1:1 randomized, global, placebo-controlled study of 42 patients with subcutaneous tophi.