More information: Kazuhisa Uchida et al, Encapsulation of a Single-Stranded Form of DNA Impurities into the Capsid of a Recombinant Adeno-Associated Virus, Human Gene Therapy (2025). DOI: 10.1089 ...

This diagram illustrates the creation of recombinant DNA using a plasmid as a vector. The host plasmid is cleaved by restriction endonucleases, creating sticky ends. These sticky ends allow for the ...

along with their drug-resistance plasmid as a new, improved cloning vector to show that frog DNA could also be replicated and transcribed in E. coli. While Paul Berg received the 1980 Nobel Prize in ...

allowing for their mass production and launching recombinant biotechnology as we know it. In 1973, the Cohen-Boyer team introduced a plasmid fragment from one strain of Escherichia coli, conferring ...

Restriction endonucleases are often used in research to cut and paste DNA sequences in a plasmid. For example, if you wish the recombinant protein to bind an antibody and also produce a ...

It serves as a comprehensive solution for the development and manufacturing of non-monoclonal antibody (non-mAb) recombinant proteins and plasmid DNA for clients across the globe - EffiX ...

Scientists are always looking for ways to better human lives, and the use of recombinant DNA (rDNA) is one of their methods. Like with anything, though, there are pros and cons to rDNA technology.

It was the first drug produced through recombinant DNA technology and among the first genetically engineered products to be available to consumers. Following the success of Humulin, recombinant DNA ...

DNA impurities from plasmid and host cell DNA are encapsulated as single-stranded DNA within recombinant adeno-associated virus (rAAV) capsids. These impurities pose a quality control challenge in ...

The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...