最后，随着RNA生物学的不断发展，AS在肺部疾病治疗中的研究也将持续深入。未来，我们或许能够看到更多针对AS的创新药物问世，为患者带来新的希望。总而言之，RNA剪接作为肺部疾病治疗的新兴领域，展现出广阔的前景与应用潜力。 返回搜狐，查看更多 ...

这篇综述聚焦转录后 rna 剪接，详细探讨其在真核生物中的重要作用。转录后剪接是基因表达调控关键环节，参与发育、应激反应及疾病进展过程。文中介绍检测方法、调控机制，分析其对健康细胞和疾病状态下基因表达程序的影响，值得研读。

哈尔滨医科大学梁海海教授团队系统阐述了AS在肺癌、肺炎、哮喘、慢性阻塞性肺疾病、肺动脉高压和特发性肺纤维化等肺部疾病中的分子调控网络与临床价值。该综述深入探讨了AS事件作为复杂疾病治疗新靶点的重要意义，并全面解析了RNA剪接在肺部疾病中的前沿突破与诊 ...

癌症治疗领域迎来重磅发现！科学家们锁定了一种意想不到的"肿瘤身份证"——由RNA剪接错误（mis-splicing）产生的新抗原（neoantigen）。在剪接因子突变的髓系恶性肿瘤中，这些异常拼接的蛋白质片段就像癌细胞特有的"分子条形码"，为精准免疫治疗提供了理想靶点。

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences ...

RNA splicing, a process discovered in the late 1970s, allows cells to precisely control the content of the mRNA transcripts that carry the instructions for building proteins.

What Is RNA Splicing?RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains ...

Initiation of the FALCON-HD trial follows promising Phase 1 results demonstrating up to 72% reduction in HTT mRNA in healthy volunteers The SKY-0515 Phase 1 trial in patients with Huntington's disease ...

Fred Hutch and MSK researchers showed that tumors driven by hiccups in RNA processing can't hid from the immune system. In work published in Cell, the team showed they could isolate T cells that ...

This “toxic RNA” depletes the protein and prevents it from binding to other RNA molecules in important areas of the genome, causing a protein imbalance which results in mis-splicing other genes.