RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

In a phase 1 trial, patients with pancreatic ductal adenocarcinoma who were treated with surgery and bespoke neoantigen mRNA vaccines combined with anti-PD-L1 and chemotherapy exhibited marked ...

STAR-RSEM pipeline based on: https://github.com/BD2KGenomics/toil-scripts/blob/releases/2.0.x/src/toil_scripts/rnaseq_cgl/README.md Annotations, Reference genome and ...