We introduce a melded chemical and computational approach for probing and modeling higher-order intramolecular tertiary interactions in RNA. 2′-Hydroxyl molecular interference (HMX) identifies ...

After the discovery of the RNA interference (RNAi) mechanism, the development of siRNA-based gene therapy has been accelerated immensely. siRNA-based treatment for hereditary transthyretin-mediated ...

Chemists have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth -- a key process in the origin of life. Skip to main content Your source for the latest research news ...

The company inked a deal with the ophthalmological drug developer Bausch + Lomb in January to develop RNA-interference (RNAi) drugs for retinal diseases including geographic atrophy.

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth – a key process in the origin of life.

Determination of the PAN ENE triple helix structure, revealing its functionally important sequence and structural features, facilitated identification of multiple additional ENE-like elements through ...