Our cells rely on microscopic highways and specialized protein vehicles to move everything—from positioning organelles to ...

Much of the difficulty of determining the contributions of individual residues to protein structure and function stems from the need to generate and evaluate a large number of mutants. The ...

For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt create folds and pockets that can accomplish the remarkably improbable: driving chemical ...

estimation of the effect that genetic mutations have on protein structure and function, modeling of (and potentially interference with) the interfaces of proteins that create (perhaps unwanted ...

A research team has identified a molecular mechanism that coordinates the operation of the N-methyl-D-aspartate (NMDA) ...

A study from VIB-KU Leuven reveals how the interaction between the proteins GPR158 and PLCXD2 regulates synaptic maturation.

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read ...

Until now such synonymous changes in DNA were deemed “silent” mutations that did not affect the structure or function of the resulting protein. Chemists at Pennsylvania State University have ...

A study has found that an ancient protein motif that binds to nucleic acids is functionally "ambidextrous." This means that ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

Protein is one of the body’s main building blocks. It plays a key role in the structure and function of muscles, skin, enzymes, and hormones. Protein deficiency is when your intake is unable to ...