Much of the difficulty of determining the contributions of individual residues to protein structure and function stems from the need to generate and evaluate a large number of mutants. The ...

The information DNA contains is the instructions that the cell uses to make proteins. Proteins play a big part in determining the characteristics of specialised cells and whole organisms.

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read ...

New research by scientists at the University of Toronto and the Structural Genomics Consortium has deepened our understanding ...

In the subsequent years, DeepMind created the AlphaFold Protein Structure Database, which now includes over 200 million structures. Access to these protein structures opened the door to a deeper ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

The study shows how subtle changes in a protein’s sequence, within just a few non-active site amino acid residues, can lead ...

In today’s digital transformation era, scientific inquiry is increasingly guided by computational tools that uncover intricate biological mechanisms. Sarika Kondra, along with co-authors Feng Chen, ...

Hyderabad: Scientists at the Centre for Cellular and Molecular Biology (CCMB) have recently made a significant discovery: ...

The new model, called BaseFold, enables more reliable 3D structure predictions for larger and more complex proteins and, according to the company, is “poised to greatly accelerate AI-based drug ...