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Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that have a number of important physiological roles including remodelling of the extracellular matrix, facilitating cell migration, ...
Background: Matrix metalloproteases (MMPs) are believed to be important in the pathogenesis of cigarette smoke-induced emphysema, but this hypothesis has only been proved in the mouse and its ...
Here, the aim was to develop an ACPP sensitive to matrix metalloproteinase-2 and -9 (MMP-2/9) for nuclear imaging purposes. MMP-2/9 ACPPs and non-activatable cell-penetrating peptides (non-ACPP) were ...
SR9009 was found to exert REV-ERB–independent effects on proliferation, metabolism, and gene transcription in 2 different cell types depleted of REV-ERBs. Therefore, effects of these drugs cannot be ...
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